Impact of phototherapy type and duration on serum electrolytes and blood glucose in neonatal hyperbilirubinemia: a prospective single-center cohort study

Abstract Background Neonatal hyperbilirubinemia (NH) is among the common neonatal morbidities. Phototherapy its most used therapeutic intervention. Different delivering systems and types are currently available. This study aimed to detect compare effects of different phototherapy on serum electrolytes blood glucose effect duration them. Results Five hundred healthy newborns with indirect NH were treated by (conventional, light emitting diode LED, intensive) according severity availability. Serum sodium (Na), potassium (K), calcium (Ca), urea nitrogen (BUN), creatinine (Cr), (Glu) measured repeatedly over 48 h phototherapy. In this prospective cohort study, 273 (54.6%) neonates exposed conventional phototherapy, 145 (29.0%) 82 (16.4%) intensive A highly significant negative correlation was found between levels Na, K, Ca, BUN, Cr ( p < 0.001). There a positive level = 0.005). Each type individually significantly affected Bun, Cr, Ca after h. Comparing 3 together, no differences apart from decline in at 0.043) recorded. Conclusions decreased during These changes duration. The had only some potassium.